PDG dry granulation advised as a valid alternative to the wet granulation of standard procedures in the processing of active pharmaceutical ingredients often their technological limits unless the wet granulation, the principally or the direct injection. The Finnish company of Atacama Labs – – sets with his pneumatic dry granulation process successfully, however, and supplies free-flowing granules of virtually any active pharmaceutical ingredient. The so-called PDG technology (= pneumatic dry granulation) helps pharmaceutical developers with significantly expanded (solution) possibilities of the galenic formulation. New York Museums: the source for more info. The PDG granulate offers a number of advantages over conventional methods such as improvement of flowability and Compactability, disintegration and dissolution. In addition, tablets can be fitted with a higher dose of the active ingredient (70% to 90%). Tablets are small, thereby simplifying the intake. The Great Depression has much to offer in this field.
Also in fixed combinations, the high Drugload plays a crucial role. There are advantages of this technology by the way not only for the galenical development, but also for the actual industrial production process. Significant cost savings up to 30%, processing steps, continuous production and a high input / output ratio, label the production method of the Finnish innovation company of Atacama Labs. Also the scale-up of the laboratory and the production happens easily. “Managing Director Steffen Mittwich puts it in a nutshell: with our PDG method succeeds, to offer a simple, cost-effective, and highly reliable it production method, which significantly facilitates new developments in the pharmaceutical industry and helps to overcome problems in the product development.” Topical now scientific findings are available to traditionally difficult to manufacturing products: ibuprofen, paracetamol, metformin and microcrystalline cellulose. It has been proven that these products can be processed for ideal flowable resin with excellent Kompaktiereigenschaften about dry granulation. The resulting tablets showed very satisfactory hardness, and Friabilitatsprofile without capping and dissolution properties and excellent DIS integration in the test (s.a. publications poster) it creates with its novel PDG method to improve the product life cycle (life-cycle-management”) the company from Helsinki, to give drug companies new product information and product opportunities, as well as to provide active ingredients in highly concentrated form in previously unknown quality to the market. Information: Steffen Mittwich Atacama Labs Oy Fredrikinkatu 61 6th floor 00100 Helsinki Finland Tel.